Estimation of Expected time to Seroconversion of HIV infected when the Antigenic Diversity Thresholds has SCBZ Property

AUTHOR AND
AFFILIATION

1U. NIYAMATHULLA, 2R. ELANGOVAN and 3R. SATHIYAMOORTHI
1Department of Bio-Statistics, Vinayaka Mission College of Nursing, Karaikal – 609 609, Tamilnadu (INDIA)
2,3Department of Statistics, Annamalai University, Annamalainagar- 608 002,Tamilnadu (INDIA)
Email: srelangovan@rediffmail.com

KEYWORDS:

Seroconversion, Antigenic Diversity Threshold, Virulence, SCBZ property.

Issue Date:

April 2014

Pages:

ISSN:

2319-8044 (Online) – 2231-346X (Print)

Source:

Vol.26 – No.1

PDF

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DOI:

jusps-A

ABSTRACT:

The likelitime at which the seroconversion of HIV infected takes place is a vital event indicating the progression of the infection. The antigenic diversity of the invading antigens due to successive contacts increases and similarly the virulence also increases. The seroconversion occurs if either the total antigenic diversity crosses the threshold level or the total virulence crosses the threshold level. Using the shock model approach the expected time to seroconversion has been derived by several authors. In this paper it is assumed that the antigenic diversity threshold is a random variable which has a distribution that has the change of parameter this is called the SCBZ property. The expected time to seroconversion is obtained using this concept numerical illustrations are also provided.

Copy the following to cite this Article:

1U. NIYAMATHULLA, 2R. ELANGOVAN and 3R. SATHIYAMOORTHI, “Estimation of Expected time to Seroconversion of HIV infected when the Antigenic Diversity Thresholds has SCBZ Property”, Journal of Ultra Scientist of Physical Sciences, Volume 26, Issue 1, Page Number , 2016


Copy the following to cite this URL:

1U. NIYAMATHULLA, 2R. ELANGOVAN and 3R. SATHIYAMOORTHI, “Estimation of Expected time to Seroconversion of HIV infected when the Antigenic Diversity Thresholds has SCBZ Property”, Journal of Ultra Scientist of Physical Sciences, Volume 26, Issue 1, Page Number , 2016

Available from: http://www.ultrascientist.org/paper/157/


The likelitime at which the seroconversion of HIV infected takes place is a vital event indicating the progression of the infection. The antigenic diversity of the invading antigens due to successive contacts increases and similarly the virulence also increases. The seroconversion occurs if either the total antigenic diversity crosses the threshold level or the total virulence crosses the threshold level. Using the shock model approach the expected time to seroconversion has been derived by several authors. In this paper it is assumed that the antigenic diversity threshold is a random variable which has a distribution that has the change of parameter this is called the SCBZ property. The expected time to seroconversion is obtained using this concept numerical illustrations are also provided.